INFUSE Rate Calculator

The CLINIMIX Injections INFUSE calculator is designed to help you evaluate which of your CLINIMIX and CLINIMIX E Injection formulas can appropriately meet the prescribed nutritional goals for your patient. Simply enter your patient's weight and daily goals for protein, calories, fluid volume, and IV Fat Emulsion (hung as a piggyback).

Note: The infusion rate and all subsequent calculations for each selected CLINIMIX or CLINIMX E Injection formula are driven by the amount of CLINIMIX or CLINIMIX E Injection solution needed to meet the daily protein goal.

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CLINIMIX Inj. is a source of amino acids and dextrose. CLINIMIX E Inj. is a source of amino acids with electrolytes and dextrose with calcium. Maintenance vitamins, additional electrolytes, and trace elements are not included and should be administered as required.

This tool does not constitute medical advice and is not a substitute for good clinical judgment. It is essential that a carefully prepared protocol based on current medical practices be followed, preferably by an experienced team. Refer to the Full Prescribing Information and Important Risk Information on CLINIMIX.com.

• Step 1
• Step 2
• Step 3

Weight:		kg
Goal protein:		gm / kg / day
Goal calories:		kcal / kg / day
Goal volume:		mL / day
What percentage of IV fat emulsion (IVFE) would you like to use?
none  10%  20% IVFE volume:mL / day

CLINIMIX Inj. % Amino Acids / % Dextrose 2.75 / 5 4.25 / 5 4.25 / 10 4.25 / 20 4.25 / 25 5 / 15 5 / 20 5 / 25

CLINIMIX E Inj. % Amino Acids / % Dextrose 2.75 / 5 2.75 / 10 4.25 / 5 4.25 / 10 4.25 / 25 5 / 15 5 / 20 5 / 25

How do you want electrolyte information displayed?

Ions    -or-    Salts

In what unit(s) of measurement do you wish to see results? (check all that apply)

mEq / L mEq / kg mEq / day

Step 1: Patient Information	Patient Weight: kg	Goal protein: gm / kg / day
	Goal calories: kcal / kg / day	Goal volume: mL / day
	IVFE volume: 0 mL / day	IVFE percentage: 0%

Step 2: Selected Formulas

Indications

CLINIMIX and CLINIMIX E Injections are indicated as a caloric component in a parenteral nutrition regimen and as the protein (nitrogen) source for offsetting nitrogen loss or for treatment of negative nitrogen balance in patients where:

• The alimentary tract cannot or should not be used,
• Gastrointestinal absorption of protein is impaired, or
• Metabolic requirements for protein are substantially increased, as with extensive burns.

Important Risk Information

• It is essential that a carefully prepared protocol based on current medical practices be followed, preferably by an experienced team. Frequent clinical evaluation and laboratory determinations are necessary for proper monitoring during administration.
• CLINIMIX and CLINIMIX E Injections are contraindicated in patients having intracranial or intraspinal hemorrhage, in patients who are severely dehydrated, in patients hypersensitive to one or more amino acids and in patients with severe liver disease or hepatic coma. Solutions containing corn-derived dextrose may be contraindicated in patients with known allergy to corn or corn products.
• Because of the potential for life-threatening events, caution should be taken to ensure that precipitates have not formed in any parenteral nutrient admixture.
• Use with caution when administering to patients with anuria or renal insufficiency, pulmonary insufficiency, or heart disease. The intravenous administration of these solutions can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states, or pulmonary edema.
• Metabolic complications have been reported, such as acid-base, electrolyte, and blood glucose imbalances, elevated liver enzymes, and osmotic diuresis and dehydration.
• Other adverse reactions that may occur include febrile response, infection at the site of injection, extravasation, and hypervolemia. The infusion of hypertonic nutrient injections into a peripheral vein may result in vein irritation, vein damage, and thrombosis.
• This product contains aluminum that may be toxic with prolonged parenteral administration if kidney function is impaired.
• CLINIMIX and CLINIMIX E Injections must be admixed prior to infusion.